A Sensitive and Selective Method for Determination of Aesculin in Cortex Fraxini by Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Application in Pharmacokinetic Study

A rapid and sensitive method for determining aesculin of Cortex fraxini in rat was developed using high-performance liquid chromatography (HPLC) quadrupole time-of-flight (QTOF) tandem mass (MS/MS). Rat plasma was pretreated by fourfold methanol to remove plasma proteins. Chromatographic separation...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yi, Guo, Hui, Wu, Yinying, Geng, Qianqian, Dong, Danfeng, Wu, Huili, Li, Enxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800655/
https://www.ncbi.nlm.nih.gov/pubmed/24187648
http://dx.doi.org/10.1155/2013/432465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800655/
https://www.ncbi.nlm.nih.gov/pubmed/24187648
http://dx.doi.org/10.1155/2013/432465

Ejemplares similares