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A Sensitive and Selective Method for Determination of Aesculin in Cortex Fraxini by Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Application in Pharmacokinetic Study

A rapid and sensitive method for determining aesculin of Cortex fraxini in rat was developed using high-performance liquid chromatography (HPLC) quadrupole time-of-flight (QTOF) tandem mass (MS/MS). Rat plasma was pretreated by fourfold methanol to remove plasma proteins. Chromatographic separation...

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Detalles Bibliográficos
Autores principales:	Li, Yi, Guo, Hui, Wu, Yinying, Geng, Qianqian, Dong, Danfeng, Wu, Huili, Li, Enxiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800655/ https://www.ncbi.nlm.nih.gov/pubmed/24187648 http://dx.doi.org/10.1155/2013/432465

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