Single domain intrabodies against WASP inhibit TCR-induced immune responses in transgenic mice T cells

Intrabody technology provides a novel approach to decipher the molecular mechanisms of protein function in cells. Single domains composed of only the variable regions (V(H) or V(L)) of antibodies are the smallest recombinant antibody fragments to be constructed thus far. In this study, we developed...

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Detalles Bibliográficos
Autores principales: Sato, Mitsuru, Sawahata, Ryoko, Sakuma, Chisato, Takenouchi, Takato, Kitani, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801110/
https://www.ncbi.nlm.nih.gov/pubmed/24141565
http://dx.doi.org/10.1038/srep03003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801110/
https://www.ncbi.nlm.nih.gov/pubmed/24141565
http://dx.doi.org/10.1038/srep03003

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