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Single domain intrabodies against WASP inhibit TCR-induced immune responses in transgenic mice T cells
Intrabody technology provides a novel approach to decipher the molecular mechanisms of protein function in cells. Single domains composed of only the variable regions (V(H) or V(L)) of antibodies are the smallest recombinant antibody fragments to be constructed thus far. In this study, we developed...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801110/ https://www.ncbi.nlm.nih.gov/pubmed/24141565 http://dx.doi.org/10.1038/srep03003 |