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Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis

The epidermal growth factor receptor (EGFR) plays an essential role during development and diseases including cancer. Lamellipodin (Lpd) is known to control lamellipodia protrusion by regulating actin filament elongation via Ena/VASP proteins. However, it is unknown whether this mechanism supports e...

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Detalles Bibliográficos
Autores principales: Vehlow, Anne, Soong, Daniel, Vizcay-Barrena, Gema, Bodo, Cristian, Law, Ah-Lai, Perera, Upamali, Krause, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801443/
https://www.ncbi.nlm.nih.gov/pubmed/24076656
http://dx.doi.org/10.1038/emboj.2013.212