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Function of the C. elegans T-box factor TBX-2 depends on SUMOylation

T-box transcription factors are critical developmental regulators in all multi-cellular organisms, and altered T-box factor activity is associated with a variety of human congenital diseases and cancers. Despite the biological significance of T-box factors, their mechanism of action is not well unde...

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Detalles Bibliográficos
Autores principales: Huber, Paul, Crum, Tanya, Clary, Lynn M., Ronan, Tom, Packard, Adelaide V., Okkema, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3802552/
https://www.ncbi.nlm.nih.gov/pubmed/23595631
http://dx.doi.org/10.1007/s00018-013-1336-y