Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

Detalles Bibliográficos
Autores principales: Engel, Mark, Sidwell, Tom, Vasanthakumar, Ajithkumar, Grigoriadis, George, Banerjee, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3803129/
https://www.ncbi.nlm.nih.gov/pubmed/24187564
http://dx.doi.org/10.1155/2013/617595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3803129/
https://www.ncbi.nlm.nih.gov/pubmed/24187564
http://dx.doi.org/10.1155/2013/617595

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