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Obese melanocortin-4 receptor-deficient rats exhibit augmented angiogenic balance and vasorelaxation during pregnancy

While obesity is a major risk factor for preeclampsia, the mechanisms linking obesity and hypertension during preeclampsia remain unclear. Hypertension in preeclampsia is associated with placental ischemia-induced release of antiangiogenic soluble fms-like tyrosine kinase (sFlt-1) into the maternal...

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Detalles Bibliográficos
Autores principales: Spradley, Frank T, Palei, Ana C, Granger, Joey P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804345/
https://www.ncbi.nlm.nih.gov/pubmed/24159378
http://dx.doi.org/10.1002/phy2.81