Migrating bubble during break-induced replication drives conservative DNA synthesis

The repair of chromosomal double strand breaks (DSBs) is crucial in the maintenance of genomic integrity. However, the repair of DSBs can also destabilize the genome by causing mutations and chromosomal rearrangements, the driving forces for carcinogenesis and hereditary diseases. Break induced repl...

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Detalles Bibliográficos
Autores principales: Saini, Natalie, Ramakrishnan, Sreejith, Elango, Rajula, Ayyar, Sandeep, Zhang, Yu, Deem, Angela, Ira, Grzegorz, Haber, James E., Lobachev, Kirill S., Malkova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804423/
https://www.ncbi.nlm.nih.gov/pubmed/24025772
http://dx.doi.org/10.1038/nature12584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804423/
https://www.ncbi.nlm.nih.gov/pubmed/24025772
http://dx.doi.org/10.1038/nature12584

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