HIV-1 Infection Is Blocked at an Early Stage in Cells Devoid of Mitochondrial DNA

Human immunodeficiency virus type I (HIV-1) exploits various host cellular pathways for efficient infection. Here we report that the absence of mitochondrial DNA (mtDNA) in ρ(0) cells markedly attenuates HIV-1 infection. Importantly, reduced infection efficiency in ρ(0) cells is not simply the resul...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Gaofei, Matsuura, Suzanne E., Barrientos, Antoni, Scott, Walter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804459/
https://www.ncbi.nlm.nih.gov/pubmed/24205077
http://dx.doi.org/10.1371/journal.pone.0078035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804459/
https://www.ncbi.nlm.nih.gov/pubmed/24205077
http://dx.doi.org/10.1371/journal.pone.0078035

Ejemplares similares