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HIV-1 Infection Is Blocked at an Early Stage in Cells Devoid of Mitochondrial DNA
Human immunodeficiency virus type I (HIV-1) exploits various host cellular pathways for efficient infection. Here we report that the absence of mitochondrial DNA (mtDNA) in ρ(0) cells markedly attenuates HIV-1 infection. Importantly, reduced infection efficiency in ρ(0) cells is not simply the resul...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804459/ https://www.ncbi.nlm.nih.gov/pubmed/24205077 http://dx.doi.org/10.1371/journal.pone.0078035 |