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Quantitative Analysis of α-L-Iduronidase Expression in Immunocompetent Mice Treated with the Sleeping Beauty Transposon System

The Sleeping Beauty transposon system, a non-viral, integrating vector that can deliver the alpha-L-iduronidase-encoding gene, is efficient in correcting mucopolysaccharidosis type I in NOD/SCID mice. However, in previous studies we failed to attain reliable long-term alpha-L-iduronidase expression...

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Detalles Bibliográficos
Autores principales:	Aronovich, Elena L., Hall, Bryan C., Bell, Jason B., McIvor, R. Scott, Hackett, Perry B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804460/ https://www.ncbi.nlm.nih.gov/pubmed/24205141 http://dx.doi.org/10.1371/journal.pone.0078161

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