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Evaluation of Metabolomic Changes as a Biomarker of Chondrogenic Differentiation in 3D-cultured Human Mesenchymal Stem Cells Using Proton ((1)H) Nuclear Magnetic Resonance Spectroscopy

PURPOSE: The purpose of this study was to evaluate the metabolomic changes in 3D-cultured human mesenchymal stem cells (hMSCs) in alginate beads, so as to identify biomarkers during chondrogenesis using (1)H nuclear magnetic resonance (NMR) spectroscopy. MATERIALS AND METHODS: hMSCs (2×10(6) cells/m...

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Detalles Bibliográficos
Autores principales: Jang, Moo-Young, Chun, Song-I, Mun, Chi-Woong, Hong, Kwan Soo, Shin, Jung-Woog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804484/
https://www.ncbi.nlm.nih.gov/pubmed/24205199
http://dx.doi.org/10.1371/journal.pone.0078325