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Alcohol Interacts with Genetic Alteration of the Hippo Tumor Suppressor Pathway to Modulate Tissue Growth in Drosophila

Alcohol-mediated cancers represent more than 3.5% of cancer-related deaths, yet how alcohol promotes cancer is a major open question. Using Drosophila, we identified novel interactions between dietary ethanol and loss of tumor suppressor components of the Hippo Pathway. The Hippo Pathway suppresses...

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Detalles Bibliográficos
Autores principales: Ilanges, Anoj, Jahanshahi, Maryam, Balobin, Denis M., Pfleger, Cathie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804493/
https://www.ncbi.nlm.nih.gov/pubmed/24205337
http://dx.doi.org/10.1371/journal.pone.0078880