Rab3a Is Critical for Trapping Alpha-MSH Granules in the High Ca(2+)-Affinity Pool by Preventing Constitutive Exocytosis

Rab3a is a small GTPase of the Rab3 subfamily that acts during late stages of Ca(2+)-regulated exocytosis. Previous functional analysis in pituitary melanotrophs described Rab3a as a positive regulator of Ca(2+)-dependent exocytosis. However, the precise role of the Rab3a isoform on the kinetics and...

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Detalles Bibliográficos
Autores principales: Sedej, Simon, Klemen, Maša Skelin, Schlüter, Oliver M., Rupnik, Marjan Slak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804518/
https://www.ncbi.nlm.nih.gov/pubmed/24205339
http://dx.doi.org/10.1371/journal.pone.0078883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804518/
https://www.ncbi.nlm.nih.gov/pubmed/24205339
http://dx.doi.org/10.1371/journal.pone.0078883

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