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Rab3a Is Critical for Trapping Alpha-MSH Granules in the High Ca(2+)-Affinity Pool by Preventing Constitutive Exocytosis
Rab3a is a small GTPase of the Rab3 subfamily that acts during late stages of Ca(2+)-regulated exocytosis. Previous functional analysis in pituitary melanotrophs described Rab3a as a positive regulator of Ca(2+)-dependent exocytosis. However, the precise role of the Rab3a isoform on the kinetics and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804518/ https://www.ncbi.nlm.nih.gov/pubmed/24205339 http://dx.doi.org/10.1371/journal.pone.0078883 |