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Novel Tools to Analyze the Function of Salmonella Effectors Show That SvpB Ectopic Expression Induces Cell Cycle Arrest in Tumor Cells

In order to further characterize its role in pathogenesis and to establish whether its overproduction can lead to eukaryotic tumor cell death, Salmonella strains able to express its virulence factor SpvB (an ADP-ribosyl transferase enzyme) in a salicylate-inducible way have been constructed and anal...

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Detalles Bibliográficos
Autores principales: Mesa-Pereira, Beatriz, Medina, Carlos, Camacho, Eva María, Flores, Amando, Santero, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804527/
https://www.ncbi.nlm.nih.gov/pubmed/24205236
http://dx.doi.org/10.1371/journal.pone.0078458