Production and First-in-Man Use of T Cells Engineered to Express a HSVTK-CD34 Sort-Suicide Gene

Suicide gene modified donor T cells can improve immune reconstitution after allogeneic haematopoietic stem cell transplantation (SCT), but can be eliminated in the event of graft versus host disease (GVHD) through the administration of prodrug. Here we report the production and first-in-man use of m...

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Detalles Bibliográficos
Autores principales: Zhan, Hong, Gilmour, Kimberly, Chan, Lucas, Farzaneh, Farzin, McNicol, Anne Marie, Xu, Jin-Hua, Adams, Stuart, Fehse, Boris, Veys, Paul, Thrasher, Adrian, Gaspar, Hubert, Qasim, Waseem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804528/
https://www.ncbi.nlm.nih.gov/pubmed/24204746
http://dx.doi.org/10.1371/journal.pone.0077106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804528/
https://www.ncbi.nlm.nih.gov/pubmed/24204746
http://dx.doi.org/10.1371/journal.pone.0077106

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