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Induction of DARPP-32 by Brain-Derived Neurotrophic Factor in Striatal Neurons In Vitro Is Modified by Histone Deacetylase Inhibitors and Nab2

Neurotrophins and modifiers of chromatin acetylation and deacetylation participate in regulation of transcription during neuronal maturation and maintenance. The striatal medium spiny neuron is supported by cortically-derived brain derived neurotrophic factor and is the most vulnerable neuron in Hun...

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Detalles Bibliográficos
Autores principales: Chandwani, Samira, Keilani, Serene, Ortiz-Virumbrales, Maitane, Morant, Andrika, Bezdecny, Steve, Ehrlich, Michelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804529/
https://www.ncbi.nlm.nih.gov/pubmed/24204683
http://dx.doi.org/10.1371/journal.pone.0076842