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Atomic-Accuracy Prediction of Protein Loop Structures through an RNA-Inspired Ansatz

Consistently predicting biopolymer structure at atomic resolution from sequence alone remains a difficult problem, even for small sub-segments of large proteins. Such loop prediction challenges, which arise frequently in comparative modeling and protein design, can become intractable as loop lengths...

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Detalles Bibliográficos
Autor principal: Das, Rhiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804535/
https://www.ncbi.nlm.nih.gov/pubmed/24204571
http://dx.doi.org/10.1371/journal.pone.0074830