A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse

ETV5 (Ets variant gene 5) is a transcription factor that is required for fertility. In this study, we demonstrate that ETV5 plays additional roles in embryonic and postnatal developmental processes in the mouse. Through a genome-wide mouse mutagenesis approach, we generated a sterile mouse line that...

Descripción completa

Detalles Bibliográficos
Autores principales: Jamsai, Duangporn, Clark, Brett J., Smith, Stephanie J., Whittle, Belinda, Goodnow, Christopher C., Ormandy, Christopher J., O’Bryan, Moira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804586/
https://www.ncbi.nlm.nih.gov/pubmed/24204802
http://dx.doi.org/10.1371/journal.pone.0077311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804586/
https://www.ncbi.nlm.nih.gov/pubmed/24204802
http://dx.doi.org/10.1371/journal.pone.0077311

Ejemplares similares