Single Nucleotide Polymorphisms of Human STING Can Affect Innate Immune Response to Cyclic Dinucleotides

The STING (stimulator of interferon genes) protein can bind cyclic dinucleotides to activate the production of type I interferons and inflammatory cytokines. The cyclic dinucleotides can be bacterial second messengers c-di-GMP and c-di-AMP, 3’5’-3’5’ cyclic GMP-AMP (3’3’ cGAMP) produced by Vibrio ch...

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Detalles Bibliográficos
Autores principales: Yi, Guanghui, Brendel, Volker P., Shu, Chang, Li, Pingwei, Palanathan, Satheesh, Cheng Kao, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804601/
https://www.ncbi.nlm.nih.gov/pubmed/24204993
http://dx.doi.org/10.1371/journal.pone.0077846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804601/
https://www.ncbi.nlm.nih.gov/pubmed/24204993
http://dx.doi.org/10.1371/journal.pone.0077846

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