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BIN1 Is Decreased in Sporadic but Not Familial Alzheimer’s Disease or in Aging

Bridging integrator 1 (BIN1) has been implicated in sporadic Alzheimer’s disease (AD) by a number of genome wide association studies (GWAS) in a variety of populations. Here we measured BIN1 in frontal cortex samples from 24 sporadic AD and 24 age-matched non-dementia brains and correlated the expre...

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Detalles Bibliográficos
Autores principales: Glennon, Elizabeth B. C., Whitehouse, Isobel J., Miners, J. Scott, Kehoe, Patrick G., Love, Seth, Kellett, Katherine A. B., Hooper, Nigel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804620/
https://www.ncbi.nlm.nih.gov/pubmed/24205320
http://dx.doi.org/10.1371/journal.pone.0078806