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Docking Studies of Phthalimide Pharmacophore as a Sodium Channel Blocker

Objective(s): Recently, phthalimide derivatives were designed based on ameltolide and thalidomide as they possess a similar degree of anticonvulsant potency due to their phenytoin-like profile. The ability of phthalimide pharmacophore to interact with neuronal voltage-dependent sodium channels was s...

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Detalles Bibliográficos
Autores principales: Iman, Maryam, Saadabadi, Atefeh, Davood, Asghar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804840/
https://www.ncbi.nlm.nih.gov/pubmed/24171082