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Hox genes are involved in vascular wall-resident multipotent stem cell differentiation into smooth muscle cells

Human vascular wall-resident CD44+ multipotent stem cells (VW-MPSCs) within the vascular adventitia are capable to differentiate into pericytes and smooth muscle cells (SMC). This study demonstrates HOX-dependent differentiation of CD44(+) VW-MPSCs into SMC that involves epigenetic modification of t...

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Detalles Bibliográficos
Autores principales: Klein, Diana, Benchellal, Mohamed, Kleff, Veronika, Jakob, Heinz Günther, Ergün, Süleyman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804857/
https://www.ncbi.nlm.nih.gov/pubmed/24145756
http://dx.doi.org/10.1038/srep02178