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Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2

Innate lymphoid cells (ILCs) are emerging key players of the immune system with close lineage relationship to T cells. ILC2 play an important role in protective immunity against multicellular parasites, but are also involved in the pathogenesis of type 2 immune diseases. Here, we have studied the de...

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Detalles Bibliográficos
Autores principales: Gentek, Rebecca, Munneke, J. Marius, Helbig, Christina, Blom, Bianca, Hazenberg, Mette D., Spits, Hergen, Amsen, Derk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804867/
https://www.ncbi.nlm.nih.gov/pubmed/24155745
http://dx.doi.org/10.3389/fimmu.2013.00334