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Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate

In colon enterocytes and in well-differentiated colon cancer CaCo-2 cells, InsP(6) (inositol hexakisphosphate) inhibits iron uptake by forming extracellular insoluble iron/InsP(6) complexes. In this study, we confirmed that CaCo-2 cells are not able to take up iron/InsP(6) but, interestingly, found...

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Detalles Bibliográficos
Autores principales: Helmis, Christina, Blechner, Christine, Lin, Hongying, Schweizer, Michaela, Mayr, Georg W., Nielsen, Peter, Windhorst, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804887/
https://www.ncbi.nlm.nih.gov/pubmed/24050387
http://dx.doi.org/10.1042/BSR20130079