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Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy

Rational combinatorial therapeutic strategies have proven beneficial for the management of cancer. Recent success of checkpoint blockade in highly immunogenic tumors has renewed interest in immunotherapy. Regulatory T (T reg) cells densely populate solid tumors, which may promote progression through...

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Detalles Bibliográficos
Autores principales: Bos, Paula D., Plitas, George, Rudra, Dipayan, Lee, Sue Y., Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804934/
https://www.ncbi.nlm.nih.gov/pubmed/24127486
http://dx.doi.org/10.1084/jem.20130762