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Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function

Pulmonary alveolar proteinosis (PAP) results from a dysfunction of alveolar macrophages (AMs), chiefly due to disruptions in the signaling of granulocyte macrophage colony–stimulating factor (GM-CSF). We found that mice deficient for the B lymphoid transcription repressor BTB and CNC homology 2 (Bac...

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Detalles Bibliográficos
Autores principales: Nakamura, Atsushi, Ebina-Shibuya, Risa, Itoh-Nakadai, Ari, Muto, Akihiko, Shima, Hiroki, Saigusa, Daisuke, Aoki, Junken, Ebina, Masahito, Nukiwa, Toshihiro, Igarashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804940/
https://www.ncbi.nlm.nih.gov/pubmed/24127487
http://dx.doi.org/10.1084/jem.20130028