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Cgnz1 allele confers kidney resistance to damage preventing progression of immune complex–mediated acute lupus glomerulonephritis

Cgnz1 and Agnz1 on the distal region of mouse chromosome 1 are associated with chronic glomerulonephritis (cGN) and acute GN (aGN). NZM2328.Lc1R27 (R27) was generated by introgressing a C57L/J region where Cgnz1 is located to NZM2328. R27 female mice developed aGN mediated by immune complex (IC) dep...

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Detalles Bibliográficos
Autores principales: Ge, Yan, Jiang, Chao, Sung, Sun-Sang J., Bagavant, Harini, Dai, Chao, Wang, Hongyang, Kannapell, Carol C., Cathro, Helen P., Gaskin, Felicia, Man Fu, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804943/
https://www.ncbi.nlm.nih.gov/pubmed/24101379
http://dx.doi.org/10.1084/jem.20130731