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BET bromodomain inhibition suppresses T(H)17-mediated pathology
Interleukin (IL) 17–producing T helper (T(H)17) cells have been selected through evolution for their ability to control fungal and bacterial infections. It is also firmly established that their aberrant generation and activation results in autoimmune conditions. Using a characterized potent and sele...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804955/ https://www.ncbi.nlm.nih.gov/pubmed/24101376 http://dx.doi.org/10.1084/jem.20130376 |