The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokines

Infection of conventional mice with a mouse adapted (MA15) severe acute respiratory syndrome (SARS) coronavirus (CoV) reproduces many aspects of human SARS such as pathological changes in lung, viremia, neutrophilia, and lethality. However, established mouse cell lines highly susceptible to mouse-ad...

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Detalles Bibliográficos
Autores principales: Regla-Nava, Jose A., Jimenez-Guardeño, Jose M., Nieto-Torres, Jose L., Gallagher, Thomas M., Enjuanes, Luis, DeDiego, Marta L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. Published by Elsevier B.V. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805046/
https://www.ncbi.nlm.nih.gov/pubmed/23911968
http://dx.doi.org/10.1016/j.jviromet.2013.07.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805046/
https://www.ncbi.nlm.nih.gov/pubmed/23911968
http://dx.doi.org/10.1016/j.jviromet.2013.07.039

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