The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

Promoters of many developmentally regulated genes have a bivalent mark of H3K27me3 and H3K4me3 in embryonic stem cells state, which is proposed to confer precise temporal activation upon differentiation. Although Polycomb repressive complex 2 (PRC2) is known to implement H3K27me3, the COMPASS family...

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Detalles Bibliográficos
Autores principales: Hu, Deqing, Garruss, Alexander S., Gao, Xin, Morgan, Marc A., Cook, Malcolm, Smith, Edwin R., Shilatifard, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805109/
https://www.ncbi.nlm.nih.gov/pubmed/23934151
http://dx.doi.org/10.1038/nsmb.2653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805109/
https://www.ncbi.nlm.nih.gov/pubmed/23934151
http://dx.doi.org/10.1038/nsmb.2653

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