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The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

Promoters of many developmentally regulated genes have a bivalent mark of H3K27me3 and H3K4me3 in embryonic stem cells state, which is proposed to confer precise temporal activation upon differentiation. Although Polycomb repressive complex 2 (PRC2) is known to implement H3K27me3, the COMPASS family...

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Detalles Bibliográficos
Autores principales:	Hu, Deqing, Garruss, Alexander S., Gao, Xin, Morgan, Marc A., Cook, Malcolm, Smith, Edwin R., Shilatifard, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805109/ https://www.ncbi.nlm.nih.gov/pubmed/23934151 http://dx.doi.org/10.1038/nsmb.2653

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