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Dosimetry of N(6)-Formyllysine Adducts Following [(13)C(2)H(2)]-Formaldehyde Exposures in Rats

[Image: see text] With formaldehyde as the major source of endogenous N(6)-formyllysine protein adducts, we quantified endogenous and exogenous N(6)-formyllysine in the nasal epithelium of rats exposed by inhalation to 0.7, 2, 5.8, and 9.1 ppm [(13)C(2)H(2)]-formaldehyde using liquid chromatography-...

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Detalles Bibliográficos
Autores principales: Edrissi, Bahar, Taghizadeh, Koli, Moeller, Benjamin C., Kracko, Dean, Doyle-Eisele, Melanie, Swenberg, James A., Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805309/
https://www.ncbi.nlm.nih.gov/pubmed/24087891
http://dx.doi.org/10.1021/tx400320u