Synthesis of cis-C-Iodo-N-Tosyl-Aziridines using Diiodomethyllithium: Reaction Optimization, Product Scope and Stability, and a Protocol for Selection of Stationary Phase for Chromatography

[Image: see text] The preparation of C-iodo-N-Ts-aziridines with excellent cis-diastereoselectivity has been achieved in high yields by the addition of diiodomethyllithium to N-tosylimines and N-tosylimine–HSO(2)Tol adducts. This addition-cyclization protocol successfully provided a wide range of ci...

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Detalles Bibliográficos
Autores principales: Boultwood, Tom, Affron, Dominic P., Trowbridge, Aaron D., Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805312/
https://www.ncbi.nlm.nih.gov/pubmed/23738857
http://dx.doi.org/10.1021/jo400956x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805312/
https://www.ncbi.nlm.nih.gov/pubmed/23738857
http://dx.doi.org/10.1021/jo400956x

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