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Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification
[Image: see text] Most protein kinases are regulated through activation loop phosphorylation, but the contributions of individual sites are largely unresolved due to insufficient control over sample phosphorylation. Aurora-A is a mitotic Ser/Thr protein kinase that has two regulatory phosphorylation...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805324/ https://www.ncbi.nlm.nih.gov/pubmed/23924325 http://dx.doi.org/10.1021/cb400425t |