Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification

[Image: see text] Most protein kinases are regulated through activation loop phosphorylation, but the contributions of individual sites are largely unresolved due to insufficient control over sample phosphorylation. Aurora-A is a mitotic Ser/Thr protein kinase that has two regulatory phosphorylation...

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Detalles Bibliográficos
Autores principales: Rowan, Fiona C., Richards, Meirion, Bibby, Rachel A., Thompson, Andrew, Bayliss, Richard, Blagg, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805324/
https://www.ncbi.nlm.nih.gov/pubmed/23924325
http://dx.doi.org/10.1021/cb400425t

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