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Intracellular Modulation, Extracellular Disposal and Serum Increase of MiR-150 Mark Lymphocyte Activation

Activated lymphocytes release nano-sized vesicles (exosomes) containing microRNAs that can be monitored in the bloodstream. We asked whether elicitation of immune responses is followed by release of lymphocyte-specific microRNAs. We found that, upon activation in vitro, human and mouse lymphocytes d...

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Detalles Bibliográficos
Autores principales: de Candia, Paola, Torri, Anna, Gorletta, Tatiana, Fedeli, Maya, Bulgheroni, Elisabetta, Cheroni, Cristina, Marabita, Francesco, Crosti, Mariacristina, Moro, Monica, Pariani, Elena, Romanò, Luisa, Esposito, Susanna, Mosca, Fabio, Rossetti, Grazisa, Rossi, Riccardo L., Geginat, Jens, Casorati, Giulia, Dellabona, Paolo, Pagani, Massimiliano, Abrignani, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805464/
https://www.ncbi.nlm.nih.gov/pubmed/24205408
http://dx.doi.org/10.1371/journal.pone.0075348