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Diagnostic Accuracy of Quantitative PCR (Xpert MTB/RIF) for Tuberculous Meningitis in a High Burden Setting: A Prospective Study

BACKGROUND: Tuberculous meningitis (TBM) is difficult to diagnose promptly. The utility of the Xpert MTB/RIF test for the diagnosis of TBM remains unclear, and the effect of host- and sample-related factors on test performance is unknown. This study sought to evaluate the sensitivity and specificity...

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Detalles Bibliográficos
Autores principales: Patel, Vinod B., Theron, Grant, Lenders, Laura, Matinyena, Brian, Connolly, Cathy, Singh, Ravesh, Coovadia, Yacoob, Ndung'u, Thumbi, Dheda, Keertan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805498/
https://www.ncbi.nlm.nih.gov/pubmed/24167451
http://dx.doi.org/10.1371/journal.pmed.1001536