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Normal Development in Mice Over-Expressing the Intracellular Domain of DLL1 Argues against Reverse Signaling by DLL1 In Vivo

The Notch signaling pathway mediates the direct communication between adjacent cells and regulates multiple developmental processes. Interaction of the Notch receptor with its ligands induces the liberation of the intracellular portion of Notch (NICD) referred to as regulated intramembraneous proteo...

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Detalles Bibliográficos
Autores principales: Redeker, Christian, Schuster-Gossler, Karin, Kremmer, Elisabeth, Gossler, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805521/
https://www.ncbi.nlm.nih.gov/pubmed/24167636
http://dx.doi.org/10.1371/journal.pone.0079050