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Evaluating Predictive Pharmacogenetic Signatures of Adverse Events in Colorectal Cancer Patients Treated with Fluoropyrimidines

The potential clinical utility of genetic markers associated with response to fluoropyrimidine treatment in colorectal cancer patients remains controversial despite extensive study. Our aim was to test the clinical validity of both novel and previously identified markers of adverse events in a broad...

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Detalles Bibliográficos
Autores principales: Jennings, Barbara A., Loke, Yoon K., Skinner, Jane, Keane, Melanie, Chu, Gavin S., Turner, Richard, Epurescu, Daniel, Barrett, Ann, Willis, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805522/
https://www.ncbi.nlm.nih.gov/pubmed/24167597
http://dx.doi.org/10.1371/journal.pone.0078053