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Protein Denaturation with Guanidinium: A 2D-IR Study

[Image: see text] Guanidinium (Gdm(+)) is a widely used denaturant, but it is still largely unknown how it operates at the molecular level. In particular, the effect of guanidinium on the different types of secondary structure motifs of proteins is at present not clear. Here, we use two-dimensional...

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Detalles Bibliográficos
Autores principales: Huerta-Viga, Adriana, Woutersen, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805561/
https://www.ncbi.nlm.nih.gov/pubmed/24163724
http://dx.doi.org/10.1021/jz401754b