Powerful Haplotype-Based Hardy-Weinberg Equilibrium Tests for Tightly Linked Loci

Recently, there have been many case-control studies proposed to test for association between haplotypes and disease, which require the Hardy-Weinberg equilibrium (HWE) assumption of haplotype frequencies. As such, haplotype inference of unphased genotypes and development of haplotype-based HWE tests...

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Detalles Bibliográficos
Autores principales: Mao, Wei-Gao, He, Hai-Qiang, Xu, Yan, Chen, Ping-Yan, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805574/
https://www.ncbi.nlm.nih.gov/pubmed/24167573
http://dx.doi.org/10.1371/journal.pone.0077399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805574/
https://www.ncbi.nlm.nih.gov/pubmed/24167573
http://dx.doi.org/10.1371/journal.pone.0077399

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