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Powerful Haplotype-Based Hardy-Weinberg Equilibrium Tests for Tightly Linked Loci
Recently, there have been many case-control studies proposed to test for association between haplotypes and disease, which require the Hardy-Weinberg equilibrium (HWE) assumption of haplotype frequencies. As such, haplotype inference of unphased genotypes and development of haplotype-based HWE tests...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805574/ https://www.ncbi.nlm.nih.gov/pubmed/24167573 http://dx.doi.org/10.1371/journal.pone.0077399 |