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A Single Vaccination with an Improved Nonspreading Rift Valley Fever Virus Vaccine Provides Sterile Immunity in Lambs

Rift Valley fever virus (RVFV) is an important pathogen that affects ruminants and humans. Recently we developed a vaccine based on nonspreading RVFV (NSR) and showed that a single vaccination with this vaccine protects lambs from viremia and clinical signs. However, low levels of viral RNA were det...

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Detalles Bibliográficos
Autores principales: Oreshkova, Nadia, van Keulen, Lucien, Kant, Jet, Moormann, Rob J. M., Kortekaas, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805595/
https://www.ncbi.nlm.nih.gov/pubmed/24167574
http://dx.doi.org/10.1371/journal.pone.0077461