Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap

Polyadenylation of mRNA leads to increased protein expression in response to diverse stimuli, but it is difficult to identify mRNAs that become polyadenylated in living cells. Here we describe a click chemistry-compatible nucleoside analog that is selectively incorporated into poly(A) tails of trans...

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Detalles Bibliográficos
Autores principales: Curanovic, Dusica, Cohen, Michael, Singh, Irtisha, Slagle, Christopher E., Leslie, Christina S., Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805764/
https://www.ncbi.nlm.nih.gov/pubmed/23995769
http://dx.doi.org/10.1038/nchembio.1334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805764/
https://www.ncbi.nlm.nih.gov/pubmed/23995769
http://dx.doi.org/10.1038/nchembio.1334

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