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Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap
Polyadenylation of mRNA leads to increased protein expression in response to diverse stimuli, but it is difficult to identify mRNAs that become polyadenylated in living cells. Here we describe a click chemistry-compatible nucleoside analog that is selectively incorporated into poly(A) tails of trans...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805764/ https://www.ncbi.nlm.nih.gov/pubmed/23995769 http://dx.doi.org/10.1038/nchembio.1334 |