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Sirtuin Deacetylases as Therapeutic Targets in the Nervous System
Sirtuins are a conserved family of deacetylases whose activities are dependent on nicotinamide adenine dinucleotide (NAD(+)). Sirtuins act in different cellular compartments, such as the nucleus where they deacetylate histones and transcriptional factors, in the cytoplasm where they modulate cytoske...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805877/ https://www.ncbi.nlm.nih.gov/pubmed/24037427 http://dx.doi.org/10.1007/s13311-013-0214-5 |