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Memory formation for trace fear conditioning requires ubiquitin-proteasome mediated protein degradation in the prefrontal cortex

The cellular mechanisms supporting plasticity during memory consolidation have been a subject of considerable interest. De novo protein and mRNA synthesis in several brain areas are critical, and more recently protein degradation, mediated by the ubiquitin-proteasome system (UPS), has been shown to...

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Detalles Bibliográficos
Autores principales: Reis, David S., Jarome, Timothy J., Helmstetter, Fred J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805936/
https://www.ncbi.nlm.nih.gov/pubmed/24167477
http://dx.doi.org/10.3389/fnbeh.2013.00150